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Costas ARVANITIS – assistant professor at Georgia Tech. member of a scientific group who used ultrasound to develop delivery system for potent RNA drugs – is a graduate of the University of Patras holding an M.Sc. in Medical Physics, University of Patras (2005).
A multi-institutional team of researchers, led by Costas ARVANITIS at the Georgia Institute of Technology and Emory University, developed a technique using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors.
Their results are included in the paper “Y. Guo, H. Lee, Z. Fang, A. Velalopoulou, J. Kim, B. Thomas, T. Kim, A. F. Coskun, D. P. Krummel, S. Sengupta, T. McDannold, and C. D. Arvanitis. “Single-cell analysis reveals effective siRNA delivery in brain tumors with microbubble-enhanced ultrasound and cationic nanoparticles” Science Advances, April 2021” that describes the team’s development of a next-generation, tunable delivery system for RNA-based therapy in brain tumors.
Their work was supported by the National Institutes of Health (NIH), grant No. R00 EB016971 and grant No. R37 CA239039; and the CURE Foundation.
More:
https://arvanitis.gatech.edu/people/
https://bme.gatech.edu/bme/faculty/Costas-D.-Arvanitis
https://bme.gatech.edu/bme/news/breaching-blood-brain-barrier-deliver-precious-payloads
Costas ARVANITIS – assistant professor at Georgia Tech. member of a scientific group who used ultrasound to develop delivery system for potent RNA drugs – is a graduate of the University of Patras holding an M.Sc. in Medical Physics, University of Patras (2005).
A multi-institutional team of researchers, led by Costas ARVANITIS at the Georgia Institute of Technology and Emory University, developed a technique using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors.
Their results are included in the paper “Y. Guo, H. Lee, Z. Fang, A. Velalopoulou, J. Kim, B. Thomas, T. Kim, A. F. Coskun, D. P. Krummel, S. Sengupta, T. McDannold, and C. D. Arvanitis. “Single-cell analysis reveals effective siRNA delivery in brain tumors with microbubble-enhanced ultrasound and cationic nanoparticles” Science Advances, April 2021” that describes the team’s development of a next-generation, tunable delivery system for RNA-based therapy in brain tumors.
Their work was supported by the National Institutes of Health (NIH), grant No. R00 EB016971 and grant No. R37 CA239039; and the CURE Foundation.
More:
https://arvanitis.gatech.edu/people/
https://bme.gatech.edu/bme/faculty/Costas-D.-Arvanitis
https://bme.gatech.edu/bme/news/breaching-blood-brain-barrier-deliver-precious-payloads